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Stephen Shears and David Armstrong read the manuscript, and provided helpful comments
Melatonin inhibits oxidative stress-induced Ca 2+ mobilization through transient receptor potential (TRP) melastatin 2 (TRPM2) and TRP vanilloid type 1 (TRPV1) channels resulting in the prevention of mitochondrial depolarization, intracellular ROS production and apoptosis in neurons [153]
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The findings indicated that 3 weeks of LC supplementation, in the amount 2-3 g/day, effectively alleviated pain [50,51,52,53]
Tordjman S, Chokron S, Delorme R, et al
