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In the case of heavy metal poisoning (greater than 200 g L 1 of lead or cadmium within the blood), chelation therapy can be proposed to help decrease these high blood concentrations by forcing the elimination of the metals, which is most commonly performed with intravenous treatments of edetate calcium disodium (CaNa 2 EDTA) as well as 2,3-dimercaptosuccinic acid (DMSA) and sodium 2,3-dimercaptopropane 1-sulfonate (DMPS) 20,27

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Beef and dairy cattle grazing in regions known to be deficient in cobalt, copper, and selenium should be treated with a registered therapy that treats and controls that specific mineral deficiency, Kim said