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Description
demonstrated in a macrophage-specific IGF-1 Apoe -/- mouse model that macrophage-derived IGF-1 inhibited the expression of chemokine (C-X-C motif) ligand 12 (CXCL12), reduced monocyte recruitment to plaques, and favoured macrophage cholesterol efflux (60)
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In total, the round-trip trek is about 60 to 65 kilometers (37 to 40 miles), depending on the route
