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Because of this highly individualized and unpredictable immunological response, patients with severe, highly reactive MCAS should introduce NAC with extreme caution and patience

Seek medical advice if you experience persistent constipation not improving with self-care, blood in stools, unexplained weight loss, severe abdominal pain, or significant changes in bowel habits, particularly if aged over 50 with new symptoms

That fact alone causes unnecessary panic in many users who see elevated lipase or amylase on their lab results