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Peroxide Metabolism in the Erythrocyte It is the lack of NADPH that causes hemolysis of erythrocytes, because H 2 O 2 and other reactive oxygen species cannot be reduced, leading to oxidation of hemoglobin to methemoglobin and membrane damage (Ruwende and Hill 1998)

The reverse is true

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[DOI] [PubMed] [Google Scholar] 4.Ji J., Lefebvre E., Laporte J