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In certain embodiments, X 5 has a 3-phosphorothioate group with a chirality of Sp
These observations are also true for specific activity of these enzymes, as we did not observe significant changes in total protein in AH associated with POAG
Similar analogs of KG Similar analogs of KG serve as competitive inhibitors against PHDs, which include succinate, fumarase, R-2-hydroxyglutarate (R-2-HG), S-2-hydroxyglutarate (S-2-HG), etc
