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The dose-response curve was obtained after the co-administration of fixed doses of tesofensine and 5-HTP based on fractions (1/2, 1/4, and 1/8) relative to their respective ED 30 values

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Animal studies also examined the AOD9604 mechanism of action at the molecular level, confirming that the peptide works through beta-3 adrenergic receptor activation and downstream stimulation of lipolysis