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Furthermore, GSH plays a key role in various physiological processes, including signal transduction, cell proliferation, and apoptosis regulation

Ethics approval and consent to participate This study was approved by the Animal Experiment Ethics Committee of Changchun University of Chinese Medicine, with ethical approval number 2024427, and the entire experiment was supervised by this committee

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In the gut, T cells maintain immune balance, differentiating into proinflammatory (Th1, Th17) or anti-inflammatory [Th2, regulatory T cells (Tregs)] subsets ( 2.1.3 The link between gut microbiome and AD AD, based on emerging research over the past two decades, may be associated with chronic stress, where prolonged exposure to adverse life events (such as MDD and anxiety) increases the risk of developing the disease (Huang et al., 2024)