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How This Works NAD+ is a coenzyme central to redox reactions, energy metabolism (glycolysis, TCA cycle, oxidative phosphorylation), and cellular maintenance pathways including DNA repair and mitochondrial biogenesis [1]

[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Bravo-Rivera C., Roman-Ortiz C., Brignoni-Perez E., Sotres-Bayon F., Quirk G.J

Moreover, since frozen serum can be used with comparable efficacy to fresh serum (data not shown), individual-centric spheroids can be generated and analyzed in different laboratories using the same donor-derived batch under identical experimental conditions and drug treatments, to demonstrate the reproducibility and transferability of the system

Conflict of interest Flynn McGuire, Riley Martinez, Annika Lenz, Lee Skinner, and Dan Cushman declare that they have no conflict of interest