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Covalent binding to a normal protein produces a haptenprotein conjugate that is recognised as foreign by the immune system and can act as an antigen ( Fig
Oral DNA vaccination targeting VEGFR-2 combined with anti-PD-L1 avelumab in patients with progressive glioblastoma, a phase I/II study: NCT03750071
This contrasts markedly with full-length growth hormone, which can impair glucose tolerance and potentially precipitate or worsen diabetes
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