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The failure of immunomodulatory mechanisms to regulate this inflammation further exacerbates the condition (43, 44)

Immediate Steps If you suspect an allergic reaction to acetyl-L-carnitine, take these actions: Stop taking the supplement immediately to prevent worsening symptoms Take an OTC antihistamine to reduce mild allergic symptoms Seek emergency care if experiencing difficulty breathing, swelling of the face or throat, or severe symptoms Document your symptoms to share with your healthcare provider Sublingual Immunotherapy While sublingual immunotherapy is highly effective for environmental and certain food allergies, it is not currently a standard treatment for supplement allergies like acetyl-L-carnitine

This can affect how much energy we feel, how well muscles perform, and how quickly we recover

doi: 10.1038/ni.1831 175 ZhuW.GregoryJ