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Accumulation of ROS can activate the mitochondrial apoptotic pathway and induce apoptosis, and esculetin can block this process by scavenging ROS (32)

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In Encyclopedia of Stress (pp

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Enhances skin texture, elasticity, and wound healing

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Iron exhibits redox activity and engages in the production of intracellular free radicals and lipid peroxides ( via the Fenton reaction, which means reactions of Fe 2+ and peroxides to generate oxygen-centered radicals (Winterbourn, 1995)

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