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Description
Fudosteine is a cysteine derivative with better bioavailability than NAC, and has been shown to increase cellular cysteine, decrease goblet cell hyperplasia, inhibit MUC5AC mucin secretion and gene expression in the rat airway

Furthermore, the NPs can be readily surface-modified with diverse organic compounds, ligands, and other agents to achieve target specificity, augmenting their efficacy

10.3389/fcell.2024.1422520

Macrophages in the mucus layer can rapidly recognize and engulf inhaled therapeutics, leading to premature clearance or degradation
