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Increased levels of kynurenine and decreased levels of arginine, sarcosine and LPC were also observed as the top-performing metabolites for identifying COVID-19 positive patients from healthy control subjects 11

Metabolism of such oxo-aldehydes through the glyoxalase system involves conjugation to GSH, catalyzed by glyoxalase 1

That SFN injected directly into Arabidopsis leaves has been reported to lead to a rapid decrease of the cellular glutathione pool 75 further strengthens the involvement of glutathione in ITC-triggered growth inhibition
