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Besides, in rats with inflamed intestines, PER downregulated the toll-like receptor 4 (TLR4), NF-B, and c-Fos/c-Jun pathways at the molecular level (Sayed et al
Kao SJ, Wang D, Lin HI, Chen HI
doi: 10.1211/jpp.59.4.0004
"Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome." Human molecular genetics 22, no
