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GSH-dependent activation releases Cu + to engage lipoylated DLAT and simultaneously unmasks glucose oxidase activity, inducing nutrient deprivation and triggering cuproptosis 216
63, 5660.10.1016/0304-3940(86)90012-1 290 YoudimM
Crystals can be taken up by mesenchymal dendritic cells via phagocytosis, a process that triggers the assembly and activation of NLRP3 inflammatory vesicles, leading to the release of IL-1, which in turn triggers the release of NF-kB-dependent cytokines and chemokines, amplifying the inflammatory response [323]
H., Lin, Y., Corales, E
