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In Summary: 12 times per week is the most common and safe schedule for MIC+B12 shots Max 3 per week only if prescribed for short-term use Review after 46 weeks to assess results and adjust frequency Glutathione Typical Frequency Guidelines Administration Method Matters subcutaneous (SubQ) - (Max 1ml) intramuscular (IM) - (Max 3ml) For IM use of 200 mg/mL, most people get 1 mL per shot, though some protocols go up to 6001200 mg per week total