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8 The significance of the above discoveries is not lost on AFSA

136 1701-1705 (American Institute of Nutrition, 2006)

The healthy participant population within the Simcyp simulator was modified to include ~17% intermediate CYP2D6 metabolizers and ~83% extensive CYP2D6 metabolizers based on the urinary log (dextromethorphan/dextrorphan) ratios of the clinical study participants (data not shown)
