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Transgenic cystic fibrosis mice exhibit reduced early clearance of Pseudomonas aeruginosa from the respiratory tract

Approved pharmacological treatments (e.g., long-acting muscarinic antagonists, long-acting beta-agonists, corticosteroids) display the limited ability to halt disease progression mainly because they do not significantly tackle the underlying inflammation

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However, it should be remembered that information from the person, about which drug was taken, how much and the time of overdosing, is frequently unreliable