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Duchane J

Al fijarse al dominio extracelular, provoca autofosforilacin de residuos de tirosina y reclutamiento de sustratos IRS-1/IRS-2, disparando dos rutas principales: la va PI3K/Akt, asociada a supervivencia celular, captacin de glucosa e inhibicin de la apoptosis, y la va MAPK/ERK, vinculada a proliferacin y crecimiento

What makes IGF-1 LR3 unique is its ability to bypass IGF-binding proteins (IGFBPs), which usually limit IGF-1s effects

Similarly, the 337 GA polymorphism has shown associations with oxidative stress markers, primarily through elevated MDA levels seen among individuals with AA and AG genotypes in comparison with the GG genotypes