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The Dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML

Acute brain damagetrauma and ischemia Acute trauma, ischemia and stroke are characterized by prominent increases in the presence and activity of Cx43 hemichannels in astrocytes, contributing to the secondary damage of the nervous tissue 478

A provisional patent application was filed in September 2016

RNase A ribonucleases and host defense: an evolving story
