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Metagenomic sequencing directly sequences the total DNA of the sample and can simultaneously study bacteria, fungi, and viruses
2 The response to hypoxia is transcriptionally regulated by the transcription factor (TF) hypoxia inducible factor-1A ( HIF1A )

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In addition, T2D is the result of a complex interaction of environmental and genetic factors, being difficult to establish the role of each one in the pathogenesis of diabetes and in the levels of IGF-1
