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The study of the intestinal microbiota reveals that it is constantly evolving in response to host as age, nutrition (the role of rich-calorie foods in obesity), lifestyle (alcoholic beverage abuse), hormonal changes, inherited genes, epigenetic modifications, and underlying disease (NAFLD and ALD as possible examples) are major determinants of the human microbiome at any given point in time (Ogunrinola et al., 2020)

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