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Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

Since CPP-CAND was designed to interfere with the FOXO4-p53 interaction, we investigated the disruption of FOXO4-p53bp1 foci in the nucleus of senescent cells after CPP-CAND treatment

Nicastro, N., Nencha, U., Burkhard, P

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