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Mechanism of inhibition of the ATpase domain of human topoisomerase II by 1,4-benzoquinone, 1,2-naphthoquinone, 1,4-naphthoquinone, and 9,10-phenanthroquinone

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Truthfully, we are a long way from following standards utilized in the EU and banning questionable artificial food colors

Interestingly, this led to the suggestion that, since no targeted therapy has been developed to date for Marfan syndrome, the prevention or reversal of the SirT1 GS-ylated state may represent a new therapeutic strategy to prevent the dissection/rupture of the TAA in these subjects [55]