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Patients using these medications may require monitoring for changes in medication effectiveness or gastrointestinal tolerability

The powder is not water soluble (it clumps) and weighs about 2.6 grams per level measuring teaspoon

Journal of Oncology Practice , 13 (4), 233241

In addition, betaine can also be synthesized de novo from dietary choline in the mammalian liver and kidney via a two-step enzymatic process in which choline is first oxidized to betaine aldehyde by choline dehydrogenase
