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The advent of programmed death-ligand 1/programmed death-1 (PD-L1/PD-1) checkpoint blockade immunotherapy represents a paradigm shift in the management of tumours

Another important example of drug activation and inactivation is observed in the GST superfamily, which is a group of detoxifying enzymes that function to protect cellular macromolecules from electrophilic compounds

Lone et al., 2018

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