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( B and C ) IC 50 curve of rapamycin on RP ( B and C ) and MRD cells ( C ) and their parental counterpart cells
doi: 10.1016/j.tem.2005.01.004 68
Recent pre-clinical studies have suggested that Wallerian-like degeneration is driven by sterile alpha and toll/interleukin-1 receptor motif-containing 1 (SARM1) ( + hydrolase that triggers the loss of axons and neuronal cell death, and both SARM1 and its intrinsic NADase activity are required for injury-induced axon degeneration (Essuman et al., 2017
Singvogel, K
