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Teduglutide: Teduglutide is a GLP-2 analog with a glycine substitution at position 2 that confers DPP-4 resistance, extending half-life from 7 minutes to 2-3 hours

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41,155 As previously mentioned, leptin may increase the expression of the 5-HT 2B receptor in astrocytes via the LepR/JAK2/STAT3 pathway, and fluoxetine may be more effective in increasing BDNF levels and alleviating depressive-like behaviors due to the leptin-mediated increase in 5-HT 2B receptor expression

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You need it for neurotransmission

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In this study, we aimed to investigate the impact and potential underlying mechanism of ST in the context of CIRI

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