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There are several theories regarding underlying mechanisms
For instance, elevated CHAC1 mRNA levels are associated with increased recurrence risk in these cancers, underscoring its clinical relevance ( Pan-cancer analyses reveal that CHAC1 expression is highly variable, being upregulated in many cancers (e.g., breast, ovarian, lung, bladder carcinomas) and downregulated in others (e.g., certain head/neck, kidney, and brain cancers) (Sun et al., 2024
Kenyon, Camillo Ricordi, Per-Olof
& Fonseca, V
