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Probably the most important cause of asthma exacerbations are viral infections [417], which can be partially avoided by vaccinations, if available

Epub 2013 Aug 16

Cardiovasc Res 36:276281 Masaki I, Yonemitsu Y, Yamashita A, Sata S, Tanii M, Komori K, Nakagawa K, Hou X, Nagai Y, Hasegawa M et al (2002) Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2

Other strengths included allowing for appropriate time following administration of anaesthetic before biomechanical and functional testing to ensure that there was no interference between measures