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This pathway generates pentose sugar for synthesis of amino acid and nucleic acid and converts glucose to ribulose-5-phosphate via retrieving the carbon from the pentose phosphate shunt.78 Vitamin B2 (Riboflavin) plays an important role in many biologically important redox reactions such as energy producing, biosynthetic, detoxifying and electron scavenging pathways as a precursor of coenzyme flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) (9-10)

J Immunol 155:21232133 Fowlkes JL, Serra DM, Bunn RC et al (2004) Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes