hypothyroidism and l carnitine L-carnitine supplementation at doses of 2–4 g/day has been shown in a randomized, double-blind, placebo-controlled trial by Salvatore Benvenga to reverse prevent symptoms of iatrogenic hyperthyroidism in women receiving TSH-suppressive levothyroxine The Role of L-Carnitine in
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Glycine is also involved in the modulation of excitatory neurotransmission exerted via glutamate binding to N -methyl-D-aspartate (NMDA) type glutamate receptors

And the treatment depends entirely on the reason

MiR-206 may suppress non-small lung cancer metastasis by targeting CORO1C

Using a pad with a hole in the center can alleviate the symptoms, but surgical intervention might be considered
