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While many of the studies used animal models and have not been proven in humans yet, clinical trials are ongoing

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Miller A.J., Arnold A.C

Mechanism of regulation of intestinal epithelial tight junction proteins A crucial function of IECs is the maintenance of barrier integrity, which allows the permeability of essential ions, nutrients, and water but restricts the entry of bacterial toxins and pathogens 21