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Description
J Free Radic Biol Med
Puerarin, a natural flavonoid, alleviates ulcerative colitis in mice by reducing inflammation, balancing cytokines, maintaining intestinal barrier integrity, restoring immune function, inhibiting NF-B and NLRP3 inflammasome activation, and reducing oxidative stress
the latter is hydrolyzed to monoglutamate via a reaction mediated by folate conjugase at the brush border of enterocytes in the proximal small intestine
Briefly, washed RBCs were incubated with a 2 M working concentration of 2,7 dichlorofluorescin diacetate (DCFDA) for 30 minutes
