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Vitamin B12 (B12) is an essential cofactor for two enzymes involved in onecarbon metabolism: methylmalonyl CoA mutase (reduced function of this enzyme results in increased serum methylmalonyl acid (MMA) levels) and methionine synthetase (this enzyme catalyzes the remethylmation of homocysteine to methionine)

The NRV of vitamin B12 for adults is set at 2.5g/day in the UK. 10% to 30% of adults older than 50 years often have B12 malabsorption syndromes, driving absorption rates as low as 1% of the ingested B12. Thus, those adults would need to ingest 240 g of B12 to absorb at least 2.4 g

GHK-Cu dose for wound healing and tissue repair GHK-Cu accelerates angiogenesis , drives collagen deposition and reduces inflammation
