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Gut microbiota composition and diversity were evaluated using 16S rRNA gene sequencing

The Charaka Samhita and Sushruta Samhita describe Kutki as a potent bitter tonic (tikta rasa) that alleviates ama (toxins), supports digestion, and calms Pitta-related imbalances
Urinary 8-hydroxy-2-deoxyguanosine levels increase after reperfusion in acute myocardial infarction and may predict subsequent cardiac events

doi:10.1089/ars.2014.5837 Woolley JF, Stanicka J, Cotter TG (2013) Recent advances in reactive oxygen species measurement in biological systems