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Preclinical studies in AMD animal models and clinical trials are warranted for confirmation of Gyps' beneficial effects against AMD

H consistently demonstrated protective effects against apoptosis, fibrosis, inflammation, and oxidative stress across acute kidney injury, nephrotoxicity, transplantation, and early chronic kidney disease models

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Since dietary glycation products are a major source of the total AGE pool in the body, reducing their absorption through their degradation in the gastrointestinal tract becomes critically important for preventing potential AGE-related harmful effects