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The changes in renal function that are common after trauma and major surgery may lead to several-fold changes in the plasma concentrations of these substances (125), which renders the reliability of these markers questionable

Mature results of a randomized trial of two doses of cisplatin for the treatment of ovarian cancer
doi: 10.1080/19490976.2015.1134082 106 BlachierFAndriamihajaMLarraufiePAhnELanAKimE

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