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Half-life means the time it takes for the concentration of the drug in your bloodstream to decrease by exactly 50 percent

2 without any vacuum followed by centrifugation and dried in an oven (Thermo Fisher Scientific, United States) at 40C

Beta-oxidation: the burning of fats Once inside the mitochondria, fatty acids are released and enter a process called beta-oxidation : they are progressively "broken down" into smaller units (acetyl-CoA), which then fuel the Krebs cycle and the respiratory chain to produce ATP (the cell's energy currency)

Hyperosmotic stress, a condition commonly associated with DE due to tear film instability, has been shown to increase the expression of senescence markers such as p53, p21, and p16 [155]