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Both compounds also decreased the mass of brown adipose tissue in lean and obese mice, suggesting a broader effect on adipose tissue metabolism [2]

Retatrutide for type 2 diabetes: Phase 2 trial results (36-week study, HbA1c reductions, weight loss) New England Journal of Medicine (2023) Jastreboff AM, et al

However, cagrilintide and tirzepatide work through entirely different receptor systems
