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Given in vitro efficacy and lack of cytotoxicity of GSH-MEE, the researchers suggested the development of GSH-MEE, instead of GSH, as an efficacious and safe molecule for the treatment of hyperpigmentation [22]
Mice were exposed to progressively increased concentrations of ethanol as described above
Iron metabolism also contributes to LPO-induced ferroptosis in melanoma [133]
The complex interplay of these hits is illustrated in Figure 1, which summarizes the sequential and overlapping mechanisms underlying MASLD pathogenesis
