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Therefore, the model provides a platform from which the impact of varying degrees of quinone concentration and exposure times on GSH homeostasis may be computationally examined

Tanaka, H., et al., E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

In conclusion, V-9302, a glutamine uptake inhibitor, not just enhanced the anti-tumor function of CD8 + T cells, but also induced immune escape by up-regulating the expression of PD-L1 in tumor cells, indicating that V-9302 had a complex effect on the immune response (Fig