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Further, we used Tween 80 and Span 20 as the surfactant and co-surfactant, respectively
It is crucial to develop new delivery methods and synthetic analogs that can enhance this critical aspect: although there are already some, further clinical trials are needed to investigate the bioavailability of polyphenols with innovative methods, like enriched foods containing free or encapsulated polyphenols [100]
doi: 10.1016/j.intimp.2012.03.006
For facial skin improvement, topical is often sufficient
