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This is, unfortunately, a common occurrence as we age Vegan or vegetarian diet as most B12 foods are from animal sources Excessive alcohol consumption Toxic metal exposure Some Auto-immune conditions Certain genetic polymorphism Some medications like antacids, anti-histamines, and some blood-sugar-lowering drugs

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In addition, it allowed the detection of residual disease after therapy, which is important for prognosis and is often used as an endpoint in clinical trials of MM

The difference between cyanocobalamin and methylcobalamin is that in methylcobalamin a methyl group replaces the cyano group
