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Regardless of the underlying molecular mechanism, most pathogenic variants yield substantially decreased or null activity of CBS
For women in their 40s who are still cycling or just entering perimenopause, the peptide answer is different
Additionally, a PDZ domain in the proteins COOH terminus was found to help retain the protein at the basolateral membrane (Greenough et al., 2004)
Chemotherapy is a potentially life-extending treatment, and chemotherapy-induced peripheral neuropathy (CIPN) is one of its most common long-term toxicities
