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In order to test this hypothesis, the group synthesized 2-[[2-[4-(3-oxo-1,2-benzoselenazol-2-yl)phenyl]acetyl]amino]ethyl-triphenyl-phosphonium chloride (mitoperoxidase 2) derivative and evaluated its efficacy for ameliorating radiation toxicity in cellular and mice models (Table 2) (Fig

It is worth noting that thiostreptozotocin promotes ferroptosis by downregulating GPX4 mRNA and GPX levels mainly by decreasing intracellular STAT3 and p-STAT3 expression rather than affecting SLC7A11 protein expression [140]

Response of Jonagold apple trees to Ca, K and Mg fertilization in an andisol in southern Chile

This opens the way for the development of other rational, hypothesis-based therapies