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More than half of the patients were former smokers (12 of 23, 52%), and the average BMI was 35.32 kg/m 2 , classified as class II obesity, with 70% (16/23) being obese

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However, conventional oral B12 supplements, such as cyanocobalamin and methylcobalamin, face significant challenges during their transit through the GI tract (23)

Well explore the molecular basis of this selectivity, compare it to full-length growth hormone and other interventions, examine the clinical evidence for its targeted effects, and discuss practical implications for individuals seeking fat loss without metabolic or endocrine disruption