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These biological processes are closely associated with connective tissue function and structural recovery in laboratory models

APX differs from other peroxidases in its dependency on ASC as the source of reducing power and becomes unstable in its absence (Shigeoka et al., Arabidopsis has 9 APX genes (AtAPX1-AtAPX6, sAPX, tAPX, lAPX) and Oryza sativa has 8 isozymes ( Os APX1- Os APX8), having two APX each in cytosol, peroxisome, chloroplast and mitochondria (Table 1)

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On the other hand, a low ROS state shows an OXPHOS-dominated M2 metabolic mode, featured by efficient ETC and reduced ROS production, which is conducive to the maintenance of M2 polarization and facilitates anti-inflammatory and repair functions (90)