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In particular, the mitochondrial SOD (MnSOD/SOD2) converts .O 2 . into H 2 O 2 , which is less reactive than .O 2 . and so can readily be used for cellular signalling

Amongst them, HK-II has been found to be specifically expressed in RA synovial lining and has a function in regulating FLS aggressiveness, and overexpression of HK-II leads to an increased ability of FLS migration and invasion (45)

In vivo, pretreatment with DBP-Lip-Gel resulted in smoother skin, with histopathological analysis showing a marked reduction in epidermal thickening

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